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Journal: bioRxiv
Article Title: Spatially-resolved single cell atlas of liposarcoma reveals lineage hierarchies, immune niches, and regulatory circuits
doi: 10.64898/2026.03.23.713651
Figure Lengend Snippet: (A) PCA analysis of H3K27Ac CUT&RUN data. (B) Correlation heatmap analysis between biological replicates. (C) Differential peak analysis identified 1109 H3K27Ac peaks enriched in WDLPS and 676 peaks enriched in DDLPS. (D) Track plots of CUT&RUN analysis showing H3K27Ac enrichment at CD34, F3, ICAM1, KIT, PDGFRA, YAP1 loci comparing the bigwig tracks of DDLPS and WDLPS samples (n=3) (E) Schematic showing the core regulatory circuits identified in sclerotic WDLPS and DDLPS with corresponding target genes.
Article Snippet: Sequencing libraries were prepared with 5 ng DNA (or total recovered if less) and the
Techniques: